NanoLC Products & Reviews

The Waters IdentityE High Definition Proteomics system defines the new standard for rigorous protein identification. The IdentityE High Definition Proteomics System is an UltraPerformance LC® (UPLC)/High-Bandwidth Mass Spectrometry (MS E) system solution suitable for confident protein identification designed to meet stringent requirements as outlined by leading scientific journals.The new Waters IdentityE High Definition Pro…

The EXP® Nano Trap System is designed to remove detergents or salts which can affect the ionization process in MS work rated for routine use up to 20,000 psi.The new nano-scale traps are available in two formats – EXP® Nano Trap and EXP® Nano Trap HR. Both formats are available in 10 or 20 mm lengths and in a variety of bed volumes ranging from 0.25µL - 4.0µL. The EXP® Nano Trap follows a traditional trap column format, design…

The EXP® Hand Tight Nano Fittings System offers hand-tight and hex head adjustable nut and ferrule compression fittings for extreme pressure connections between 1/32” stainless steel tubing and 6-40 ports.Ideal for nano-scale UHPLC and UHPLC/MS, this nut and ferrule compression fitting is rated to 20,000+ psi (1400+ bar). The patent-pending EXP® 1/32” Titanium Hybrid Ferrule combines the sealing capability of PEEK and robust n…

The EXP® Nano Fittings System offers hand-tight and hex head adjustable nut and ferrule compression fittings for extreme pressure connections between 1/32” stainless steel tubing and 6-40 ports.Ideal for nano-scale UHPLC and UHPLC/MS, this nut and ferrule compression fitting is rated to 20,000+ psi (1400+ bar). The patent-pending EXP® 1/32” Titanium Hybrid Ferrule combines the sealing capability of PEEK and robust nature of ti…

The OPTI-LYNX™ Quick Connect Trap Columns allow you to quick-connect to any 10-32 valve/port for trapping or analytical column for pre-column filtration. With OPTI-LYNX™, accessing and changing the insert takes only a quarter turn. Replace traps, filters or change configurations in seconds, without tools. OPTI-LYNX™ traps and filters (ordered separately) come in several bed volume/ diameter/ porosity combinations, allowing you…

With an internal volume of 3µL, this 50 cm long RP-C18 µPAC™ column is perfectly suited to perform high throughput analyses with shorter gradi­ent solvent times (30, 60 and 90-minute gradients) and it can be used over a wide range of flow rates, between 100 and 2000 nL/min. µPAC™ column, 50 cm length, with pillar array backbone at interpillar distance of 2.5µm, C18.

To interface the µPAC™ column with the Easy-spray source, a customized EASY-Spray™ Emitter was developed, which is now distributed by PharmaFluidics. To ensure straightforward and plug and spray connectivity, this emitter line has been provided with a low volume stainless steel connecting union that fits directly onto the µPAC™ column fittings.

Our µPAC™ Trapping column was developed with an identical stationary phase support morphology, matching perfectly the retentive properties of our analytical µPAC™ columns. Effectively desalting and preconcentrating the analytes improves the analytical column lifetime and workflow throughput.

Because the column is meanly made out of silicon which is semi-conductive, a dramatic impact on the chromatographic behavior of our µPAC™ columns has been observed if no appropriate precautions are taken in case the column is connected to an ESI source of a mass spectrometer. Therefore we developed a custom made grounding cable to shunt the high voltage to ground.

Our µPAC™ columns are provided with 1/32” fittings to be compatible with any third party LC system. To connect the column into a 1/16” valve an additional capillary containing 1/16” pre-assembled fittings is provided.