Biomarkers Products & Reviews

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Biomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :

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GFAP Simoa Assay Kit

Quanterix

Glial Fibrillary Acidic Protein (GFAP) is a class-III intermediate filament majorly expressed in astrocytic glial cells in the central nervous system. Astrocytes play a variety of key roles in supporting, guiding, nurturing, and signaling neuronal architecture and activity. Monomeric GFAP is about 55kD. It is capable of forming both homodimers and heterodimers; GFAP can polymerize with other type III proteins or with neurofila…

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NEUROLOGY 4-PLEX E (Aβ40, Aβ42, GFAP*, Nf-L)

Quanterix

The Simoa Human Neurology 4-Plex E (N4PE) assay simultaneously measures four biomarkers in EDTA plasma and CSF. The targets are Abeta 40 (Aβ40), Abeta 42 (Aβ42), Glial Fibrillary Acidic Protein (GFAP™), and Neurofilament light (Nf-L). Each biomarker has been demonstrated to have significance for the investigation of neurodegeneration and brain injury, and to have utility for monitoring effectiveness of drug discovery and devel…

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NEUROLOGY 2-PLEX B (Nf-L, GFAP*)

Quanterix

The Simoa Human Neurology 2-Plex assay (N2PB) measures two important neurology biomarkers in both cerebrospinal fluid (CSF) and blood. The two targets are neurofilament light (Nf-L) and glial fibrillary acidic protein (GFAP™), which have been studied as indicators of traumatic brain injury (TBI) severity. N2PB has been developed as a 2-Plex version of the Neurology 4-Plex B assay (N4PB). *Banyan GFAP™ is a registered tradem…

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Luminex® INTELLIFLEX DR-SE, Dual Reporter from Luminex

Bio-Techne

The Luminex xMAP INTELLIFLEX is an advanced platform for accurate protein measurement in a compact instrument. With an option for a second reporter laser, it allows detection of two parameters on a single bead, maximizing data points and sample processing. Designed for high throughput, it is the most advanced Luminex instrument. Compatible with R&D Systems Luminex assays and Quantist Analysis Software.

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FLEXMAP 3D® from Luminex

Bio-Techne

The FLEXMAP 3D is a versatile and powerful multiplexing platform from Luminex. Fast read time, compatibility with 96- and 384-well plates, and ease of integration with front-end automation systems make the FLEXMAP 3D a reliable choice for high-throughput applications.  Compatible with R&D Systems Luminex assays and Quantist Analysis Software.

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Luminex® 200 from Luminex

Bio-Techne

The Luminex 200 utilizes principles of flow cytometry and is the gold standard for basic multiplexing protein needs. Simultaneously multiplex up to 100 analytes in a single microplate well. Delivers fast and cost-effective results on many assay formats. The Compatible with all R&D Systems Luminex assays and the Quantist Analysis Software.

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Human Protein S-Nitrosylation Array G1

RayBiotech Inc.

The RayBiotech G-Series Human Protein S-Nitrosylation Antibody Array 1 is a multiplex assay on glass slide for the relative detection of cystein s-nitrosylation of 507 different human proteins cell lysate, culture supernatant, serum, plasma and other biological samples.

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Human Protein Oxidation Array G1

RayBiotech Inc.

The RayBiotech Human Protein Oxidation Antibody Array 1 is a multiplex assay on glass slide for the relative detection of oxidation of 507 different human proteins in cell lysate, culture supernatant, serum, plasma and other biological samples.

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Human Protein S-Acylation Array G1

RayBiotech Inc.

The RayBiotech Human Protein S-Acylation Antibody Array 1 is a multiplex assay on glass slide for the relative detection of cystein s-acylation of 507 different human proteins cell lysate, culture supernatant, serum, plasma and other biological samples.

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Multispecific Antibody Development

Sino Biological

Sino Biological offers a wide range of products and services to provide customers with complete multispecific antibody development solutions covering various phases of the development process, such as antibody development and optimization, druggability assessment, animal model evaluation, and process development.

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Comprehensive Toolkits for SARS-CoV-2 Variants Research

Sino Biological

Sino Biological has developed a series of high-quality research reagents for dominant SARS-CoV-2 mutants, including recombinant antigens, detection antibodies, ELISA kits, pseudovirus, cDNAs, peptide pools, and receptor ACE2. These variant reagents have actively supported the basic research of SARS-CoV-2 and the development of vaccines, therapeutic antibodies, and diagnostic reagents.

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Cytokine Target Proteins

Sino Biological

Cytokines and their receptors show great potential in tumor immunotherapy, and many cytokines have been identified as targets for tumor drug development. Sino Biological's cytokines support stem cells, neural cells, immune cells, and organoids, facilitating functional studies and accelerating scientific discoveries.

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Recombinant CEACAM Proteins

Sino Biological

Sino Biological provides a comprehensive range of recombinant CEACAM proteins and corresponding CEACAM antibodies for crucial research, aiding investigations into CEACAM interactions with pathogens and their potential in new medical discoveries.

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MILLIPLEX® MAP Human Cancer Biomarker Panel

Merck

Millipore now proudly offers the MILLIPLEX® MAP Human Cancer Biomarker Panel. The Cancer Biomarker Panel includes both a Five-Plex assay, which simultaneously measures five serum biomarkers, Macrophage Migration Inhibitory Factor (MIF), Prolactin, CA-125, Leptin and Osteopontin (OPN), and a Single Plex IGF-II assay. The combination of the six serum biomarkers that discriminate between disease-free and ovarian cancer patien…

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