Cell Death / Health Assays
The Guava Caspase Assay Suite of fluorescent-based assays for Caspase 3/7, 8, 9 and multi-caspase employ the same protocol making it easier to perform multiple caspase assays in parallel. Further, Guava caspase reagents are membrane permeable allowing one to measure intracellular levels of the enzyme without using harsh lysis methods. The Guava Caspase Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspase) reagent th…
This kit enables simultaneous measurements in the same cell of six independent parameters that monitor cell health, including cell loss, nuclear size and morphological changes, mitochondrial membrane potential changes, cytochrome c release, and changes in cell permeability.
The BrdU and Ki67 Cell Proliferation HCS Reagent Kits are for simultaneous quantification of DNA replication and Ki67 proliferation marker in the same cell.
The Multiparameter Cell Death Detection Kits for high-content screening (HCS) enable simultaneous quantitation of LC3B protein on autophagic vesicles, cytochrome c localization and its release from mitochrondria, cell membrane integrity and its permeability and nuclear morphology and DNA content.
The micronucleus assay is an important component of genetic toxicology screening programs. Micronuclei arise from acentric chromosomes and lagging whole chromosomes.
The Autophagy & Proteasome Function: LC3B and Poly-Ubiquitin Detection Kits enable quantitation of LC3B protein on autophagic vesicles and ubiquitin on polyubiquitinated proteins.
The Cellomics Phospho-ATM Activation Kit contains optimized reagents for the detection and quantitation of phosphorylated ATM (Ser1981) in the nuclei.
The Mitotic Index HCS Reagent Kit provides high-content screening (HCS)-quality fluorescence reagents and a validated protocol for measurement of mitotic index, or the fraction of cells undergoing cell division within a population.
Micro-ruled coverslip for cell culture with microscopic identification and measurement markers.
BlueScreen HC is based on the fast, accurate GreenScreen HC genotoxicity assay from Gentronix Ltd. BlueScreen HC uses the same human-derived, p53-competent TK6 cells to host a patented reporter system that exploits the proper regulation of the GADD45a gene. However, in place of GFP, BlueScreen HC utilizes a luciferase from the marine copepod Gaussia princeps to generate a luminescent output. The BlueScreen luminescent assa…
