Cell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.
A new secondary messenger for Gq coupled receptor investigation.Cisbio’s IP-One assay, based on its proprietary HTRF® technology, is the first HTS immunoassay that can easily detect inositol(1)phosphate (IP1), a stable second messenger which tightly correlates with Gq-coupled receptor activity. This assay displays all the characteristic advantages of an HTRF® system: totally homogeneous, detection via fluorescence, signal stab…
For general laboratory use. The MagNA Pure LC Total Nucleic Acid Isolation Kit – Lysis/Binding Buffer Refill is designed for lysis of mammalian blood, serum, or plasma samples, and the stabilization of nucleic acids. After the addition of Lysis/Binding Buffer to the sample, the cells are lysed and enzymes (e.g., ribonucleases) are effectively inactivated. The lysed and stabilized samples can be immediately processed (or aft…
For use with:Cat. No. 03 172 627 001 MagNA Pure LC mRNA Isolation Kit II (Tissue) orCat. No. 03 330 591 001 MagNA Pure LC RNA Isolation Kit III (Tissue) For general laboratory use. The MagNA Pure LC RNA Isolation Tissue Lysis Buffer – Refill is designed for lysis and homogenization of fresh frozen tissue samples using a tissue homogenizer (see the MagNA Lyser Instrument) stabilization of total RNA and mRNA within samp…
For general laboratory use. The MagNA Pure LC mRNA Isolation Kit I - Lysis Buffer Refill is designed to lyse mammalian whole blood, blood cells, or cultured cells, and stabilize mRNA.After the addition of Lysis Buffer to the sample, the cells are lysed and enzymes (e.g., ribonucleases) are effectively inactivated. The lysed and stabilized samples can be immediately processed (or after long-term storage) with the MagNA Pure LC…
For use with the MagNA Pure Compact Nucleic Acid Isolation Kit I For general laboratory use. The MagNA Pure Bacteria Lysis Buffer is designed for: lysis of bacteria in many different samples of mammalian origin (e.g., urine, bronchoalveolar lavage [BAL], sputum, cerebrospinal fluid [CSF], swabs) or bacterial cultures stabilization of DNA in sample lysates purification of bacterial DNA with the MagNA Pure Compact Instru…
GFP/RFP-Booster – enhance your fluorescent fusion protein ChromoTek’s Booster are very small, highly specific GFP- or RFP-binding proteins covalently coupled to the superior fluorescent dyes from ATTO-TEC. With our Booster you can: • Reactivate • Boost • Stabilize the signals of your fusion proteinsDirectly stain your protein of interest in fixed cells and benefit from the high specificity an small size that are perfect for su…
Chromobodies® - Your perfect reagents for cellular research including High-Content Analysis. Chromobodies are fluorescent nanoprobes suitable for real time analyses of endogenous cellular structures and processes in live cells. Chromobodies® are a novel species of extremely small intracellular antibodies. They are based on the antigen binding domain (VHH) derived from heavy chain antibodies of camelids genetically fused to a f…
DNA methylation was the first epigenetic modification identified and has been intensively studied for more than half a century. By now it is clear that Dnmt1, the major eukaryotic DNA methyltransferase, faithfully maintains genome-wide methylation patterns and plays an essential role in the epigenetic network controlling gene expression and genome stability during development. However, the molecular mechanisms that ultimately…
Being able to visualize endogenous cellular structures in live cells is key for many high content analyses. The two Chromobodies® of the ChromoTek’s Cell Organelle Toolbox offer a new way to investigate key compartments of the cell non-invasively. Lamin-Chromobody® The new Lamin-Chromobody® is a major breakthrough especially in High-Content Analysis (HCA) as apoptosis assays thus far rely on static endpoint assays. The nucle…
The VenaT4™ biochip model combines Cellix's proprietary microfluidic flow technology for cell recruitment under shear stress with traditional transwell chamber models. Used to investigate and quantify cell recruitment to various ligands in the presence of chemoattractants contained within the microwells mimicking tissue and / or injury sites. The biochips contain 4 microcapillaries in parallel, each with an embedded microporo…
