Biomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :
Glial Fibrillary Acidic Protein (GFAP) is a class-III intermediate filament majorly expressed in astrocytic glial cells in the central nervous system. Astrocytes play a variety of key roles in supporting, guiding, nurturing, and signaling neuronal architecture and activity. Monomeric GFAP is about 55kD. It is capable of forming both homodimers and heterodimers; GFAP can polymerize with other type III proteins or with neurofila…
The Simoa Human Neurology 4-Plex E (N4PE) assay simultaneously measures four biomarkers in EDTA plasma and CSF. The targets are Abeta 40 (Aβ40), Abeta 42 (Aβ42), Glial Fibrillary Acidic Protein (GFAP™), and Neurofilament light (Nf-L). Each biomarker has been demonstrated to have significance for the investigation of neurodegeneration and brain injury, and to have utility for monitoring effectiveness of drug discovery and devel…
Advance your neurology research from discovery to the clinic by reliably detecting pTau-181 in plasma, serum, or cerebrospinal fluid (CSF).
The Simoa Human Neurology 2-Plex assay (N2PB) measures two important neurology biomarkers in both cerebrospinal fluid (CSF) and blood. The two targets are neurofilament light (Nf-L) and glial fibrillary acidic protein (GFAP™), which have been studied as indicators of traumatic brain injury (TBI) severity. N2PB has been developed as a 2-Plex version of the Neurology 4-Plex B assay (N4PB). *Banyan GFAP™ is a registered tradem…
The Luminex xMAP INTELLIFLEX is an advanced platform for accurate protein measurement in a compact instrument. With an option for a second reporter laser, it allows detection of two parameters on a single bead, maximizing data points and sample processing. Designed for high throughput, it is the most advanced Luminex instrument. Compatible with R&D Systems Luminex assays and Quantist Analysis Software.
The FLEXMAP 3D is a versatile and powerful multiplexing platform from Luminex. Fast read time, compatibility with 96- and 384-well plates, and ease of integration with front-end automation systems make the FLEXMAP 3D a reliable choice for high-throughput applications. Compatible with R&D Systems Luminex assays and Quantist Analysis Software.
The Luminex 200 utilizes principles of flow cytometry and is the gold standard for basic multiplexing protein needs. Simultaneously multiplex up to 100 analytes in a single microplate well. Delivers fast and cost-effective results on many assay formats. The Compatible with all R&D Systems Luminex assays and the Quantist Analysis Software.
In-depth understanding of complete genome in human, aninal, plant and microbe with end-to-end services.
Sequencing only service for customer-premade libraries at different read lengths and capacities to suit any cost, project scale and turnaround with the world-leading, powerful, and sophisticated sequencing platforms (Illumina, Pacbio, and Oxford Nanopore).
16S/18S/ITS rRNA amplicon metagenomic sequencing employs universal primers to target specific regions to identify the phylogeny and taxonomy from complex microbiomes.
