Biomarkers Products & Reviews

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Biomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :

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Single cell sequencing

Novogene

Single cell RNA sequencing uncovers the complexity of cellular diversity to employ the study of unusual cell types, cell-lineage associations, and samples of heterogeneous nature with 10x Genomics technology.

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Long-read sequencing

Novogene

Long Read Sequencing (LRS) service employs cutting-edge technologies such as Oxford Nanopore and PacBio platforms for decoding complex genomes, completing transcriptomes, exploring metagenomes, and investigating structural variations with unmatched precision.  

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Epigenome sequencing

Novogene

Novogene provides Whole Genome Bisulfite Sequencing (WGBS), Reduced Representation Bisulfite Sequencing (RRBS), Chromatin Immunoprecipitation Sequencing (ChIP-seq), RNA Immunoprecipitation Sequencing (RIP-seq), and Assay for Transposase-Accessible Chromatin Sequencing (ATAC-seq), tailored for both bulk and single-cell samples.

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pTau-217 Assay

Quanterix

The Quanterix Simoa® ALZpath p-Tau 217 Assay provides an ultrasensitive, reliable solution for detecting phosphorylated Tau 217 (p-Tau 217) in blood. This critical biomarker is essential for Alzheimer’s research, offering insights into disease progression and helping differentiate Alzheimer’s from other forms of dementia.

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GFAP Simoa Assay Kit

Quanterix

Glial Fibrillary Acidic Protein (GFAP) is a class-III intermediate filament majorly expressed in astrocytic glial cells in the central nervous system. Astrocytes play a variety of key roles in supporting, guiding, nurturing, and signaling neuronal architecture and activity. Monomeric GFAP is about 55kD. It is capable of forming both homodimers and heterodimers; GFAP can polymerize with other type III proteins or with neurofila…

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NEUROLOGY 2-PLEX B (Nf-L, GFAP*)

Quanterix

The Simoa Human Neurology 2-Plex assay (N2PB) measures two important neurology biomarkers in both cerebrospinal fluid (CSF) and blood. The two targets are neurofilament light (Nf-L) and glial fibrillary acidic protein (GFAP™), which have been studied as indicators of traumatic brain injury (TBI) severity. N2PB has been developed as a 2-Plex version of the Neurology 4-Plex B assay (N4PB). *Banyan GFAP™ is a registered tradem…

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STELLARIS SpectraPlex Microscope

Leica Microsystems Europe

SpectraPlex for STELLARIS is a comprehensive solution for 3D high-multiplex imaging in spatial biology. It provides a streamlined workflow to simplify panel creation, automate acquisition settings, and acquire data through advanced unmixing algorithms. With SpectraPlex you can ensure data quality and reliability across scales.

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