Solid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
A medium polarity sorbent with many uses, Bond Elut Cyano (CN) is ideal for applications in which extremely nonpolar compounds would be irreversibly retained on high carbon load sorbents, such as C8 and C18. This endcapped version of the cyano sorbent is best utilized when extracting analytes from an aqueous matrix.
Bond Elut DEA bears some resemblance to Bond Elut NH2 in its properties, but with a slightly lower capacity as an anion-exchange sorbent. DEA has a moderately nonpolar character due to the alkyl side chains on the amino functionality. These groups still afford a medium level of polarity, higher than C8, but less polar than C2 or CN-E.
Bond Elut Diol resembles unbonded silica as it is known for strong hydrogen bonding with analytes. 20H can also be employed in the nonpolar mode because the hydrocarbon spacer on its functional group provides enough nonpolar character for retention of hydrophobic analytes. Bond Elut Diol is a listed SPE device for the DIN 14333-1 method on benzimidazole fungicides.
Bond Elut ENV, a PS-DVB polymer, is designed for the extraction of polar organic residues. It contains 125 µm spherical particles with a high degree of cross linking, advantageous for high volume, fast flowthrough applications.
Florisil is a magnesia-loaded silica gel. Like silica, it is extremely polar in nature and ideal for the isolation of polar compounds from nonpolar matrices. The larger particle size of the sorbent enables fast flow for large sample volumes and therefore can be an attractive alternative to silica if the sample matrix is particularly viscous.
Bond Elut LMS polymeric sorbent lets you elute without having to add amine modifiers, buffers, or acids. The elimination of secondary interactions means that elution of analytes can be achieved with pure organic solvents or HPLC mobile phase-compatible solvent mixtures of low ionic strength. These characteristics are crucial to allow compatibility with LC/MS or other delicate analytical techniques.
Bond Elut Mycotoxin is a novel sorbent which cleans up food extracts for improved trichothecene and zearalenon analysis. Results are comparable or superior to competing methods, including immunoaffinity columns (IAC) and charcoal/alumina column. The sorbent is a proprietary silica-based ion exchange material.
Bond Elut NEXUS is an ultra-clean polymeric sorbent, which has bimodal porosity and a high surface area. NEXUS offers a nonpolar retention mechanism with no preconditioning required. NEXUS WCX is a weak cation-exchange sorbent that offers extra selectivity for analytes such as quaternary ammonium drugs and anabolic steroids.
Bond Elut NH2 is a weaker anion exchanger than sorbents such as SAX (a quaternary amine sorbent that is always charged), and is therefore a better choice for retention of very strong anions, such as sulfonic acids, which may retain irreversibly on a SAX sorbent. Similar to Diol an SI sorbents, Bond Elut NH2 is excellent for the separation of structural isomers.
Bond Elut PBA is a unique silica SPE sorbent containing a phenylboronic acid functionality that can retain analytes through a reversible covalent bond. This very strong covalent retention mechanism enables high specificity and cleanliness. The boronate group has a strong affinity for cis-diol containing compounds, such as catechols, nucleic acids, some proteins, carbohydrates, and PEG compounds.
Bond Elut PCB is a specially designed sorbent that allows for the facile extraction of polychlorinated biphenyl (PCB) compounds from various matrices. Desired analytes can be loaded and eluted using a simple, single solvent method before analysis by GC/ECD.
Bond Elut PH is a nonpolar bonded silica material, which exhibits a different selectivity to alkyl or aliphatic functionalized phases, such as C8 or cyclohexyl. The electron density present in the aromatic ring affords an enhancement in the retention of conjugated or aromatic ring-containing analytes due to desirable pi-pi interactions.
Bond Elut Plexa PAX sets the new performance standard in analyte cleanup and reproducibility for polar and non-polar acidic analytes. Existing polymeric anion-exchange sorbents can exhibit a broad range of ion exchange capacity from batch to batch. This leads to nonreproducible methods and compromised data.
Bond Elut PPL is a styrene-divinylbenzene (SDVB) polymer that has been modified with a proprietary nonpolar surface. PPL will retain even the most polar classes of analytes, including phenols. The large particle size allows ease of flow for viscous or particulate-rich water samples, while the high surface area and strong hydrophobicity ensure reproducible extractions with high recoveries upon elution.
Bond Elut SAX is a strong anion-exchange sorbent ideally suited for the extraction of compounds, such as carboxylic acids, which may not retain effectively on weak anion-exchange sorbents.
Bond Elut SCX is a strong cation exchanger with a very low pKa. Although the pKa is similar to Bond Elut PRS, the presence of the benzene ring in the functional group increases the potential for nonpolar interactions. This nonpolar characteristic becomes particularly important when conducting ion exchange from aqueous systems, where selectivity towards compounds exhibiting cationic and nonpolar character is seen.
Native silica is generally regarded as the most polar SPE sorbent available. Bond Elut SI is particularly effective at separating compounds with a very similar structure. Applying the analytes in a non-polar solvent, then increasing the solvent polarity by increasing the concentration of a polar modifier, such as THF or ethyl acetate, delivers effective separations.
Simplify sodium sulfate mediated drying steps by using cartridges prepacked with ACS grade, granular anhydrous sodium sulfate. Available in three formats (LRC, Bond Elut Jr, and straight barrels).
The same Bondesil sorbent packed into the industry-leading Bond Elut cartridges is available in bulk for large-scale purification or packing custom cartridges.
Chem Elut is an economical Supported Liquid Extraction choice, available in buffered and unbuffered configurations. Agilent SLE products use a broad-performance inert diatomaceous earth sorbent for rapid, general sample preparation
Empore extraction disks provide a high flow rate solution for large volume sample preparation, and are available in a variety of bonded phases. The Empore disks are available in two diameters, 47 and 90 mm. By increasing the diameter of the disk used, the disk surface area available for sample passage increases, resulting in better solvent flow rates through the disk.
EnvirElut sorbents are specially designed for the extraction of a wide range of compounds from aqueous matrices. EnvirElut herbicides, PAHs, and pesticides are available in standard SPE straight barrel cartridges, which can be used on conventional Vac Elut vacuum manifolds.
Hydromatrix is a high purity, inert diatomaceous earth sorbent available as bulk material, offering end user flexibility and an excellent diversity of applications.
Mega Bond Elut Flash cartridges offer excellent levels of performance and productivity for the purification of organic compounds, but also for scale-up, solid phase extraction. Prepacked, disposable cartridges offer greater convenience than glass columns that must be washed, dried, and repacked after every sample.
Bond Elut SPEC is a monolithic sorbent bed manufactured with ultraclean polypropylene plastic and bonded-silica impregnated on a glass fiber disc, resulting in an SPE product that delivers faster sample processing and lower costs.
