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Target Sufficiency

Inotiv

Target Sufficiency® is the ability of a target system to respond to a therapeutic. It reflects the abundance and forms of the drug target protein, as well as other key system proteins that connect the target to disease phenotypes and enable response. Assessment of the target system requires an analysis platform that can simultaneously capture multiple precise protein measurements.

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Oxyntomodulin (OXM) ELISA

Ansh Labs

OXM causes weight loss via suppression of food intake and increase in energy expenditure. OXM administration was also reported to increase heart-rate in mice. Besides regulating glucose homeostasis in monogastric animals, OXM also increases the concentration of insulin and glucose in plasma of Holstein cattle under normal physiological conditions. It has been shown that Type 2 diabetes patients have lower levels of OXM and lev…

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Bioactive IGF-I ELISA

Ansh Labs

The Ansh Labs Bioactive IGF-I kit uses a highly sensitive two-site antibody method which allows detection of bioactive IGF-I. This assay enables accurate measurement and differentiation of bioactive IGF-I from total IGF-I levels. Assessment of bioactive to total IGF-I ratio will be informative and advance our understanding of IGF-I function and regulation in different physiological and disease states.

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