A customized XF workflow for detection and characterization of mitochondrial toxicity

Learn more about the Agilent Seahorse XF Mito Tox Assay, a customized XF solution that allows the detection and quantitative assessment of compounds eliciting mitochondrial toxicity. This application note provides proof of concept and examples for compound screening, dose-response experiments using the XF Mito Tox assay, and interpretation of resulting data using the Mito Tox Index (MTI). It also presents a discussion of strategic assay design, performance metrics, and specific cases when using the XF Mito Tox Assay.