A fast and robust GC/MS/MS analysis of 203 pesticides in 10 minutes in spinach

Agilent describes two approaches for achieving robust, multiresidue pesticide analysis in 10 minutes by GC/MS/MS, while maintaining sufficient chromatographic resolution for the analysis of over 200 pesticides in spinach; a challenging high chlorophyll, fresh matrix. Results demonstrate that excellent linearity, over a calibration dynamic range of 0.1 to 1,000 ppb or 0.5 to 1,000 ppb, was achieved with the Agilent 7010C and 7000 series triple quadrupole GC/MS systems. Method robustness was shown with 700 consecutive injections of spinach extract spiked with pesticides at 20 ppb, that spanned over 175 hours of continuous running of the GC/TQ.