A Flexible Workflow for Automated Bioluminescent Kinase Selectivity Profiling

Kinase profiling is a necessary process to confirm inhibitor selectivity and assess off-target activity. The arduous task of optimizing kinase reactions and maintaining a library of enzymes often results in the outsourcing of kinase profiling activities. This poster demonstrates how ready-to-use Kinase Selectivity Profiling Systems (KSPS) combined with easy-to-use instrumentation and automated data analysis supports a streamlined workflow to enable quick and efficient in-house kinase profiling.