A Genetically Engineered Mouse for Imaging of Apoptosis in a Tissue Specific Manner

This poster shows that expression of the Caspase 3 biosensor can be achieved in several tissues. In addition it demonstrate in mouse models of cancer, that the ability to dynamically and sensitively image the activation of the Caspase 3 provides an opportunity to understand the dynamics of cell death in response to specific drugs or combination therapies.