A Novel Tumor Model for the Characterization of Ovarian Cancer Spheroids

Ovarian cancer is a pervasive malignancy affecting women of reproductive age and older which typically arises from epithelial cells in the ovaries or fallopian tubes. Unlike other cancers which are typically disseminated solely through the bloodstream, ovarian cancer depends upon the formation of multicellular aggregates for dissemination and metastasis. These aggregates, known as spheroids, detach from the primary tumor and travel to distant sites within the peritoneum in order to proliferate. To date, few model systems mimicking this transitional state have been developed. Download this poster to learn about a novel platform of 3‐D cell culture that will enable accurate assessments of spheroid biology, including the respiratory profile and resistance to hypoxia of spheroid.