A Quantitative UPLC-MS/MS Research Method for the Measurement of Paracetamol and Metabolites in Plasma

The measurement of paracetamol, also known as Acetaminophen and it's derivatives, is a valuable means of studying the effects of the drug in both animals and humans. This application note describes a sensitive, validated, UPLC-based bioanalytical method for the quantification of acetaminophen and it's five metabolites.