A Rapid Sample Preparation Method of Comprehensive Drug Panel Analytes from Oral Fluid Collection Devices using Strata®-X-CW Solid Phase Extraction (SPE)

Use of oral fluid as a drug testing matrix has steadily gained popularity due to its easy and non-intrusive sample collection procedure. The oral fluid collection device provides a buffer solution that contains a number of antibacterial agents and surfactants which acts to prevent bacterial growth and increase the analytes stability during the sample transit to testing laboratories. Presented is a fast sample preparation procedure to reduce detrimental effect of excipients present in the buffer solution of the device.