A simple quantitative method for monoclonal antibody coformulations

Monoclonal antibodies (mAbs) are well-established therapeutics for biopharmaceutical work. However, recent trends have investigated the administration of multiple mAbs for immunotherapy and passive immunization strategies. Although characterization may present unique challenges, quantitation of each individual mAb tend to rely on standard analytical workflows, but methods for drug substance of the mAb coformulation often consist of a more complex analysis. One such consideration is a simple quantitative method for the mAb coformulation.