A Universal Surface Coating for Lab-On-A-Chip and Biosensor Applications

This poster describes an alternative to traditional methods of biomolecule attachment that utilizes a metal polymer surface chemistry. Various formulations of Mix&Go particles from Anteo Technologies can modify the strength of binding, wettability and surface charge, controlling protein binding and the stability of bound biomolecules. The coating was measured using SEM, TEM, AFM and other microscopic methods. Attaching biomolecules onto solid supports is a necessary step in developing and manufacturing most in vitro diagnostics and point-of care products. However, direct immobilization of antibodies to synthetic surfaces can damage proteins and adversely impact both their structure and function.