Accelerate the development of CRISPR-edited cell line models using the Namocell Single Cell Dispenser

The advent of CRISPR has been revolutionizing how cellular models are created to improve drug discovery. In this application note from Bio-Techne, discover how Dr. Oscar Perez-Leal, Assistant Professor in the Pharmaceutical Sciences Department of the School of Pharmacy at Temple University, USA, focuses on utilizing CRISPR genome editing to modify genes for developing cellular models for drug discovery. The approach combines CRISPR and the technology termed FAST-HDR that Dr. Perez and his team developed to knock-in genes or fluorescent tags to potential drug targets or genes encoding proteins that define specific subcellular structures.