Acquire and analyze images of FUCCI spheroids on the SpectraMax MiniMax cytometer

Spheroids are small three-dimensional (3D) cellular microenvironments grown using a variety of specialized culture methods such as low-adhesion microplates. FUCCI (fluorescent ubiquitination-based cell-cycle indicator) spheroids have been developed to study cancer cell cycle progression as they allow the identification of cells in various phases of the cell cycle.

In this application note, Molecular Devices demonstrate how the MiniMax cytometer can easily acquire and analyze images of FUCCI spheroids.