AdvanceBio HIC: A hydrophobic HPLC column for monoclonal antibody variant analysis

Monoclonal antibodies (mAbs) and related products such as antibody-drug conjugates (ADCs) and bispecific antibodies (bsAbs) are the fastest-growing classes of biotherapeutics.This application note demonstrates the separation of oxidized mAb variants from their native form using the Agilent AdvanceBio HIC column.