Advancing GMP compliance with HTS: Robust virus detection in high virus, low host systems

This study highlights how short-read high-throughput sequencing (HTS), combined with QIAGEN^® CLC Genomics Workbench, enables sensitive and reproducible detection of adventitious viruses in biologics. Conducted across seven global laboratories, the multi-lab investigation demonstrates HTS’s ability to enhance viral safety testing under GMP, supporting regulatory compliance and reducing reliance on traditional animal-based assays.