Advantages of Ostro Pass-through Sample Preparation Versus Solid Supported Liquid Extraction

In this application note, a comparison is performed between Ostro Pass-through Sample Preparation and SSLE. Typical samples used in drug discovery and development with different acidic, basic and neutral properties and hydrophobicities were analyzed in this evaluation. Key areas of comparison are procedure simplicity, analyte recoveries, matrix factor (MF), and batch-to-batch reproducibility.