AI-driven label-free image analysis for assessing chemotherapeutic cytotoxicity in glial cells

In this application note, Sartorius demonstrates a robust in vitro assay using the Incucyte^® Live-Cell Analysis System and AI-driven analytics to assess the cytotoxic effects of chemotherapeutics in glioblastoma multiform (GBM) cells. The study shows concentration-dependent effects across different glial cell types and highlights the system's potential for screening therapeutic candidates. The Incucyte system offers automated analysis, accurate cell segmentation, and live/dead classification, making it a powerful tool for studying cytotoxicity in glial cells.