An LC-MS Clinical Research Method for Measuring Male Androgens in Serum

This technology brief demonstrates that the use of an online SPE system (ACQUITY® Online Sample Manager (OSM)) enables simultaneous and analytically sensitive measurement of a panel of androgens.

This clinical research method is fast and relatively simple to implement, and has the potential to analyze large numbers of samples measuring multiple androgens in a single injection. These results were achieved by using a combination of efficient online SPE sample preparation in conjunction with a high analytical sensitivity mass spectrometer.