An optimized protocol for the 2 mg/well Clarity OTX format plates

Oligonucleotides are becoming increasingly prominent in modern medicine due to their ability to modulate both gene expression and post-translational splicing of introns and exons, making them suitable for a range of therapeutics. In this application note from Phenomenex, explore the Clarity® OTX protocol which differs from other solid phase extraction (SPE) methods due to its ability to bind desired oligonucleotide analytes as well as most other components in serum (proteins, lipids, oligos, etc.)