Analysis of “Bath Salt” Compounds from Urine for Forensic Toxicology Using μElution Mixed-mode SPE Combined with UPLC/MS/MS Detection

This application note details a strategy for the successful extraction and analysis of representatives of several different classes of synthetic cathinones from human urine samples for forensic toxicology. Using mixed-mode solid phase extraction (SPE) followed by UPLC/MS/MS analysis, a panel of 10 synthetic cathinones was extracted with excellent recovery and analytical sensitivity.