Analysis of polar compounds using an Agilent InfinityLab Poroshell 120 Aq-C18 column with improved and reliable performance

In this application note, a group of polar compounds were separated on a newly developed Agilent InfinityLab Poroshell 120 Aq-C18 column. The retention loss due to pore dewetting was investigated by comparing the new InfinityLab Poroshell 120 Aq-C18 column to the current C18 phase and other superficially porous columns from various manufacturers.