Analysis of sugar alcohols and allulose using an Arc HPLC System with refractive index detection

In this application note, an analytical method was developed to detect and quantify sugar alcohols and allulose in beverages and other low-calorie products. Arc HPLC-RI was combined with an Atlantis Premier BEH Z-HILIC analytical column, which provided an increase in polar analyte retention and offered a different selectivity when compared to other hydrophilic interaction liquid chromatography (HILIC) chemistries.