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Analyzing Bevacizumab, its aggregates and fragments

28 Jun 2020

Due to the sizes of monoclonal antibodies (MAbs, about 150 kDa), size exclusion chromatography (SEC) is a standard technique for analysing MAbs such as Bevacizumab (Avastin®). In this application note, YMC’s dedicated SEC column for antibodies, YMC-SEC MAB, is used to separate the monomer antibody from its aggregates as well as from degradation products in a single run.

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