Application of MultiCyt QBeads for High Throughput Cytokine Profiling in Human Peripheral Blood Mononuclear Cells

Cytokine signaling pathways between cells are an important target across the drug discovery process, from primary screening to toxicity profiling. This application note reports on the development and validation IntelliCyt’s MultiCyt QBeads for the detection of cytokines in a high-throughput screening application on the iQue Screener. A case study is presented using QBeads to profile cytokine secretion in human peripheral blood mononuclear cells (PBMC).