Applied Robotics for Enhanced Throughput Options in Microscopy as Demonstrated by Automated Tissue Microarray (TMA) Imaging

Tissue microarrays (TMAs) provide a high throughput microscopy sampling format and have proven useful in many applications such as bio banking and archiving of biopsy and other tissue samples; disease diagnosis, classification and grading; quality control; and antibody optimization during assay development. In this study, TMAs were chosen as a model for demonstrating montage and stitching image optimization at high throughput using the Cytation™ 5 Cell Imaging Multimode Reader and BioStack 4 from BioTek.