Approaches to accelerate cell line development

In addition to serving as mini-biologics factories, the ability to manipulate innate cellular function has led to the rapid expansion of novel biologics and cell-based therapies within the biopharmaceutical industry. Despite progress in bioprocess and bioproduction, certain challenges not only slow down the process but also create uncertainty in bringing a biologic to market. There are several obstacles for which the biopharma community and equipment-reagent manufacturers need a better solution. In this white paper, Cell Microsystems shows that single cell cloning workflow mediated by CellRaft Technology not only allows easy seamless cloning due to high cell viability but also provides direct auditable images for proof of monoclonality. CellRaft Technology is designed to reduce time while increasing efficiency and success rate for accelerating the generation of research cell banks for Mabs and ATMPs.