Aseptic Identification of Polysorbates Using Handled Raman

Polysorbates are used in a variety of industries including food, cosmetics, pharmaceuticals and biopharmaceuticals. Due to industry regulations and quality standards, it is considered good practice to identify incoming materials prior to manufacturing. Polysorbates are reactive to light and air therefore packaging is usually in thick, dark, amber bottles. This makes the identification process more difficult, as opening the container to sample could compromise the sterility and quality of these materials. In this application note, handheld Raman is used to identify these materials without any sampling or preparation.