Assessing contractility of 3D iPSC-derived muscle models for safety and discovery at high-throughput using a novel, label-free magnetic detection method

3D engineered muscle tissues (EMTs) are a promising tool to study cardiac contractile deficiencies in vitro. However, EMTs pose challenges as they can be complex to fabricate and require laborious optical imaging and image processing to measure contractility.

Download this poster to explore a study with a goal to design, build, and validate an EMT platform that uses 1) facile and scalable bioengineering approaches to generate tissues from a variety of cell sources, and 2) a label-free measurement technique capable of direct contractility assessment across several tissues in parallel.