Automated Live Cell Analysis of Cell Migration Across a Microfluidic-Controlled Chemoattractant Gradient

In this application note the CellASIC^® ONIX Microfluidic Plate is used to show that microfluidic control of cell culture conditions and chemoattractant gradient formation enables precise, dynamic quantitation of cell migration in response to stimuli. The results provide a reference point from which to build upon future studies aimed at comparing the effects of signaling molecules and growth factors on the migration propensities of cells in tumors, wounds, developing tissues, immune responses, and other biological systems defined by active cell migration.