Characterization of the 3D microstructure of nanofibrous scaffolds for tissue engineering

In this application note, ZEISS presents X-ray microscopy (XRM) characterization of cross-linked electrospun gelatin nanofibers. These nanofibers are potential candidates for applications like nanofibrous scaffolds for skin regeneration and wound dressings in medical care. The note delves into the unique phase-contrast techniques, specifically using the Zernike phase plate, applicable to low atomic number materials using the laboratory-based X-ray microscope ZEISS Xradia 810 Ultra.