Characterization of the Brain-Chip R1 as a first-in-class isogenic model of the human neurovascular unit

This application note details the development and characterization of Emulate’s Brain-Chip R1, a first-in-class isogenic Organ-Chip model of the human neurovascular unit. Integrating five iPSC-derived cell types within a perfused microenvironment, the model forms a tight, stable BBB-like barrier and supports physiologically relevant studies of transport, neuroinflammation, and NVU function.