Characterization of the N-glycosylation Pattern of Antibodies by ESI - and MALDI Mass Spectrometry

This application note describes the in-depth characterization of N-glycosylation pattern in various antibody samples using two complementary mass spectrometric strategies based on both, top-down ESI-UHR-TOF and bottom-up LC-MALDI-TOF/TOF performed on the Bruker maXis™ and ultrafleXtreme™ platform, respectively.