Chiral Separation of the Fungicide Metalaxyl

Metalaxyl is a fungicide used to fight plant diseases (downey mildew) in agricultural applications. Metalaxyl is a racemic phenylamide, with two enantiomers. (R)-Metalaxyl has a higher activity (Metalaxyl-M, Mefenoxam). In Germany, Switzerland and Austria only the application of this active enantiomer is permitted. The valid determination and quantification of Metalaxyl residues is very important for monitoring food, soils and ground water. This application note demonstrates the use of CHIRAL ART Cellulose-SB from YMC to separate the enantiomers of Metalaxyl.