Efficient Chromatin Removal in Viral Vector Manufacturing Using Salt-Active Nucleases

3 Oct 2024

The presence of chromatin-associated DNA in crude viral suspensions poses significant challenges for the downstream processing (DSP) of viral vectors. Peer-reviewed studies have demonstrated that M-SAN HQ excels in removing chromatin-associated DNA at physiological salt conditions, significantly outperforming traditional nucleases like Benzonase® and Denarase®. Explore how, together with SAN HQ for high salt conditions, ArcticZymes offers solutions specifically designed to meet the distinct needs of biomanufacturers.

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