Co-optimization of Probes and Polymerases to Drive the Evolution of Targeted Sequencing

This poster demonstrates the capabilities of targeted sequence enrichment using the KAPA HTP Library Preparation Kit and KAPA HiFi HotStart DNA Polymerase. Inefficiencies in library construction and automation-unfriendly workflows have previously meant low throughput and poor performance. By combining enzymes specifically tailored for high performance NGS applications with innovative oligonucleotide probe design, improved library construction and targeted enrichment can be achieved.