Common techniques for the discovery and development of peptides and proteins

In this application note, Buchi provides an overview of the techniques involved in the discovery and development of peptides and proteins. Peptides and proteins are one of the four fundamental classes of macro-molecules found in nature. They are frequently studied for their potential as therapeutic drugs. The discovery and development of peptides/proteins includes several steps, such as isolating via rotary evaporation or freeze drying, purification via preparative chromatography, and formulation by freeze, or spray drying. To ensure an efficient workflow, it is important to understand the key parameters of each technique for a proper selection.