Comparison of TcBuster non-viral transposon system to lentiviral transduction in primary human T-cells

TcBuster™ is a commercially available hyperactive transposase that efficiently integrates multi-cistronic CAR constructs into primary human immune cells, overcoming many of the challenges associated with viral delivery. In this application note from Bio-Techne, consider the comparison of generation, phenotype, and efficacy of CAR-T cells produced using either TcBuster, a non-viral transposon system, or lentivirus.