Continuous Separation of E. coli Fermentation Broth

The CEPA LE Model, a tubular-bowl continuous centrifuge, is one of a family of separation instruments characterized by their ability to process many times the capacity of their bowl total volume without interruption. This characteristic results from a design that allows continuous feeding of a solid-liquid mixture, while simultaneously expelling the liquid component. In this bioprocess laboratory application, 4.2 liters of E. Coli fermentation broth containing 6% solids by volume were separated by CEPA LE in 22 minutes.