Corning® PureCoat™ ECM Mimetic Cultureware: Animal-Free, Synthetic Surfaces for Serum-free Culture of Adherent Cells

Culture of adherent cells typically requires the use of animal-derived components such as serum and extracellular matrix (ECM) proteins, which promote cell adhesion via cell-surface adhesion receptors. However, concerns about traceability and sourcing of these naturally-derived materials have led to the search for animal-free, serum-free defined culture environments, while still maintaining or improving growth and productivity of the cells. This application note presents synthetic Corning PureCoat ECM Mimetic Cultureware for culture of cell lines relevant for biomanufacturing.