Correlation of Angiogenesis Biomarkers with Early Metastatic Progression in NSCLC as Determined using a Multiplexed Immunoassay Kit

This application note demonstrates the utility of the MILLIPLEX® map Human Angiogenesis/Growth Factor Magnetic Bead Panel 1, based on the Luminex® xMAP® bead-based multiplexed assay platform, in the analysis of 17 targets involved in the angiogenesis pathway in a cohort of 38 patients with various stages of non-small cell lung cancer (NSCLC). The objective was to determine if the MILLIPLEX® assay is able to accurately quantify known angiogenesis targets in a practical, high throughput fashion.