Customer Evaluation of the CyBi®-Drop 3D for Screening Applications

Library screening applications require the rapid transfer of compounds and reagents into 96, 384, and 1536-well microplates. Traditionally, this has been accomplished with 96- or 384-tip automated pipettors. However, there are several advantages of utilizing a non-contact dispenser for reagents that are delivered to multiple columns of a screen, including elimination of disposable pipette tip costs, increased speed and conservation of reagents. The CyBi®-Drop 3D is well-suited for this purpose since it has a volume range of 0.5 µl to 10µl per stroke and can dispense to a pattern of columns across a plate. For these reasons, the CyBi®- Drop 3D was evaluated in the HTS Solutions Laboratory from Invitrogen for use in a screening environment.