Derivation of Oligodendrocyte Progenitor Cells from a Human Neural Stem Cell Line

Human neural stem cells (hNSCs) have been intensely studied for their therapeutic potential in neurodegenerative diseases and spinal injuries. This application note shows the development of a stable cell line that can maintain a high percentage of oligodendrocyte progenitors in culture and that could potentially yield functional, myelin-producing oligodendrocytes upon spontaneous differentiation.