ResourceLife Sciences
Determination of Inhibitor Residence Times for a Phosphodiesterase using the Transcreener® AMP2/GMP2 FP Assay
18 Aug 2015The Transcreener® assays rely on antibodies that are able to differentiate between nucleotides on the basis of subtle structural differences. This makes detection of the product nucleotide possible even in the presence of excess substrate nucleotide. This case study focuses on the biochemical characterization of a broad range of targets, using Jump Dilution protocol to make residence time determinations for Transcreener® assays.