Determination of Quantitative Protein Signatures for Ductal Carcinoma (Breast Cancer) by LC/MS Proteome Analysis

In this study, a comprehensive MS-based discovery strategy is applied for a polygenic disease. The method employs the separation and detection of non-labelled tryptic fragments by means of an LC/MS acquisition. Instrumentation used included the Waters Expression High Definition Proteomics System, made up of the nanoACQUITY UPLC System and the Q-Tof Premier Mass Spectrometer.